Teixobactin- A New Antibiotic kills pathogen without detectable resistance

Posted on: February 9th, 2015 by Ashok Bhonsle 2 Comments
As per the recent article published in Nature (January 2015), Ling L.L., et al., reported a new antibiotic – teixobactin, discovered in a screen of uncultured bacteria. Teixobactin inhibits cell wall synthesis by binding to a highly conserved motif of lipid II (precursor of peptidoglycan) and lipid III (precursor of cell wall teichoic acid). No any mutants of Staphylococcus aureus or Mycobacterium tuberculosis were found to be resistant to teixobactin. The properties of this compound suggested a path towards developing antibiotics that are likely to avoid development of resistance.Teixobactin- A New Antibiotic kills pathogen without detectable resistance.More reading: http://www.nature.com/nature/journal/v517/n7535/full/nature14098.html

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